WALLIS L. CRADDOCK, M.D.; J. HADDOCK-SUAREZ, M.D.
Clinicians who have treated tuberculous meningitis readily welcome any suggestion which may improve results of treatment in this grave condition. Since Cathie1 reported beneficial results in tuberculous meningitis from intrathecal streptokinase (a component of streptococcal fibrinolysin), several British reports2, 3 have confirmed his opinions. In many institutions in England it has become routine to use this therapy, and the major effect has been a reduction in the number of cases which develop elevated intracranial pressure and internal hydrocephalus. It has been assumed that the use of this fibrinolytic enzyme should be prophylactic, in addition to its causing the liquefaction of
CRADDOCK WL, HADDOCK-SUAREZ J. TERMINAL HYPERTHERMIA FOLLOWING INTRATHECAL STREPTOKINASE ADMINISTRATION IN A CASE OF TUBERCULOUS MENINGITIS1. Ann Intern Med. ;36:168–171. doi: 10.7326/0003-4819-36-1-168
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Published: Ann Intern Med. 1952;36(1):168-171.
CNS Infections, Infectious Disease, Mycobacterial Infections, Neurology.
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