S. K. FINEBERG, M.D.; ALEXANDER ALTSCHUL, M.D., F.A.C.P.
Hyperinsulinism, in this discussion, is defined as the state produced by excessive amounts of insulin in the body, whether the insulin is exogenous or endogenous in origin. Although the term has been widely used since it was first proposed by Harris in 19241 as indicative of the clinical state produced by excessive endogenous (spontaneous) sources of insulin, as in hypertrophy, neoplasm or functional oversecretion of the islets of Langerhans, the far more frequent occurrence of the inadvertent administration of overdoses of insulin lays greater claim to the usage and application of a name so descriptively clear in its semantics. The
FINEBERG SK, ALTSCHUL A. THE ENCEPHALOPATHY OF HYPERINSULINISM1. Ann Intern Med. 1952;36:536–550. doi: 10.7326/0003-4819-36-2-536
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Published: Ann Intern Med. 1952;36(2_Part_2):536-550.
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