HYLAN A. BICKERMAN, M.D.; GUSTAV J. BECK, M.D.
The difficulties involved in the treatment of chronic pulmonary emphysema have recently been emphasized, especially the undesirable reactions that may follow the administration of oxygen in markedly anoxic patients. Comroe1 observed the development of mental changes ranging from somnolence to coma in eight of 65 patients with mild to severe chronic anoxemia, who were given high concentrations of oxygen to breathe. Godfrey, Pond and Wood studied an emphysematous patient who became comatose within five minutes after treatment with 90 to 97 per cent oxygen, and regained consciousness with equal rapidity when oxygen was discontinued.2 Davies and Mackinnon mentioned two patients
BICKERMAN HA, BECK GJ. PHYSIOLOGIC FACTORS IN THE TREATMENT OF CHRONIC HYPERTROPHIC PULMONARY EMPHYSEMA1. Ann Intern Med. 1952;36:607–624. doi: 10.7326/0003-4819-36-2-607
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Published: Ann Intern Med. 1952;36(2_Part_2):607-624.
Chronic Obstructive Airway Disease, Pulmonary/Critical Care.
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