EDWARD B. SMITH, M.D.; THEODORE C. HEMPELMANN, M.D.; SHERWOOD MOORE, M.D.; DAVID P. BARR, M.D., F.A.C.P.
Gargoylism is a heritable and congenital condition, attributable at least in part to defects in cartilaginous development which lead to dwarfism and to numerous characteristic deformities of the skeleton. The osseous abnormalities were first described by Hunter1 in 1917. Two years later Hurler2 reported cases with similar deformities and with cloudiness of the corneae and mental deficiency. Husler,3 who is responsible for the name "dysostosis multiplex," included the condition described by Hurler in his group of degenerative dysostoses. English writers coined the term "gargoylism."4, 5, 6, 7, 8 There is some confusion in the literature in both designation and description:
SMITH EB, HEMPELMANN TC, MOORE S, BARR DP. GARGOYLISM (DYSOSTOSIS MULTIPLEX): TWO ADULT CASES WITH ONE AUTOPSY1. Ann Intern Med. ;36:652–667. doi: 10.7326/0003-4819-36-2-652
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Published: Ann Intern Med. 1952;36(2_Part_2):652-667.
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