ALVIN P. SHAPIRO, M.D.; ALBERT A. BRUST, M.D.; EUGENE B. FERRIS, M.D., F.A.C.P.
Assali, Brust et al. have recently reported a comparative study of the actions of veratrum viride (Veratrone) and tetraethylammonium chloride (TEAC) in normal and toxemic pregnancy. In all toxemic cases, the blood pressure remained elevated or fell only slightly following autonomic blockade with TEAC, but fell markedly with the intravenous administration of veratrum viride.1
Since such a consistent difference between the actions of the two drugs occurred in toxemia of pregnancy, it seemed worthwhile to carry out a similar study in patients with other types of hypertension.
Fifteen hypertensive patients were studied; these included 11 with benign
ALVIN P. SHAPIRO, ALBERT A. BRUST, EUGENE B. FERRIS. A COMPARATIVE STUDY OF THE EFFECTS OF VERATRUM VIRIDE AND TETRAETHYLAMMONIUM CHLORIDE IN HYPERTENSION(A COMPARATIVE STUDY OF THE EFFECTS OF VERATRUM VIRIDE AND TETRAETHYLAMMONIUM CHLORIDE IN HYPERTENSION*). Ann Intern Med. 1952;36:807–810. doi: 10.7326/0003-4819-36-3-807
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Published: Ann Intern Med. 1952;36(3):807-810.
Cardiology, Coronary Risk Factors, Hypertension, Nephrology.
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