DAVID M. SPAIN; DONALD W. KING
The use of antibiotics, in particular penicillin, in the treatment of subacute bacterial endocarditis has so altered the course of the disease that infection is arrested in all but 10 per cent of cases treated. Only about 10 to 20 per cent die from the complications of the disease itself. The exact rôle of the renal lesions as a cause of death in treated cases of subacute bacterial endocarditis is still not settled. A report by Christie1 on 269 patients treated with penicillin listed 73 deaths of which 8 were due to uremia. However, in a study by Pillsbury and
SPAIN DM, KING DW. THE EFFECT OF PENICILLIN ON THE RENAL LESIONS OF SUBACUTE BACTERIAL ENDOCARDITIS(THE EFFECT OF PENICILLIN ON THE RENAL LESIONS OF SUBACUTE BACTERIAL ENDOCARDITIS*). Ann Intern Med. 1952;36:1086–1089. doi: 10.7326/0003-4819-36-4-1086
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Published: Ann Intern Med. 1952;36(4):1086-1089.
Cardiology, Endocarditis, Infectious Disease, Nephrology, Streptococcal Infections.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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