ARTHUR FREEDMAN, M.D.; JOHN D. YEAGLEY, M.D., F.A.C.P.; JEAN BAILEY BROOKS, M.D.
Acute porphyria is a disease characterized by one or more of the following symptoms: intense abdominal pain, diffuse muscular aching, peripheral neuropathy, psychic disturbances and discoloration of the urine ranging from pink to purple. It differs from congenital porphyria in that the acute type frequently affects adult women, whereas the congenital type affects young boys preponderantly. Moreover, in congenital porphyria, vesicular skin lesions aggravated by exposure to ultraviolet radiation are characteristic, while the acute type has no skin manifestations whatever. Both are thought to be inheritable diseases, although the literature is not altogether convincing on this point. In both types
FREEDMAN A, YEAGLEY JD, BROOKS JB. ACUTE PORPHYRIA WITH IMPROVEMENT DURING AND FOLLOWING PREGNANCY1. Ann Intern Med. ;36:1111–1120. doi: 10.7326/0003-4819-36-4-1111
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Published: Ann Intern Med. 1952;36(4):1111-1120.
Gastroenterology/Hepatology, Liver Disease.
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