ESTELLE E. KLEIBER, M.D., F.A.C.P.
In recent years there has appeared on the market a drug named khellin, C14 H12 O5, the active principle from a native Egyptian plant, Ammi visnaga, known since ancient times as an antispasmotic. This drug has been found to be a coronary vasodilator, with apparent potency about four times that of aminophylline. It is available for oral use in doses of 20 to 50 mg. in an enteric coated tablet. An abundant literature has appeared on the oral use of this drug.1-5 However, many of these studies, while suggesting a good effect in the control of angina, report a high
KLEIBER EE. PARENTERAL ADMINISTRATION OF AMMIVIN (KHELLIN) IN THE TREATMENT OF CORONARY DISEASE1. Ann Intern Med. 1952;36:1179–1189. doi: 10.7326/0003-4819-36-5-1179
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Published: Ann Intern Med. 1952;36(5):1179-1189.
Cardiology, Coronary Heart Disease.
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