GEORGE B. MCADAMS; WILLIAM T. SALTER, F.A.C.P.
In this report are included comparative studies on approximately 45 patients whose thyroid function was appraised by four laboratory tests, in addition to routine clinical observations. These laboratory tests were:
(1) Serum "hormonal" iodine (protein-precipitable), S.H.I.
(2) Basal metabolic rate, B.M.R.
(3) 24-hour uptake of radio-iodide, I131.
(4) Thyroid secretory rate, T.S.R., which was determined by the turnover of radio-iodide in the gland, as described by Salter, de Visscher and McAdams.1
The chief objective was to validate laboratory means for distinguishing between hyperplasia and hyperfunction of the thyroid in the goitrous patient.
The patients studied comprised a wide range of
MCADAMS GB, SALTER WT. COMPARATIVE TESTS OF THYROID FUNCTION1. Ann Intern Med. ;36:1198–1205. doi: 10.7326/0003-4819-36-5-1198
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Published: Ann Intern Med. 1952;36(5):1198-1205.
Endocrine and Metabolism, Thyroid Disorders.
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