WILLIAM H. REEDER, M.D.; BEN E. GOODRICH, M.D., F.A.C.P.
Only recently, unsuspected x-ray evidence of nondescript pulmonary infiltrations has focused attention on Loeffler's syndrome, tropical eosinophilia and related conditions. Fewer than 25 case reports of Loeffler's syndrome were found by Peabody1 in English as recently as 1944. Increased use of chest roentgenography and expanded mass x-ray surveys of the general population should lead to more frequent case reports.
Sir William Osler2 was probably first to report pulmonary abnormality associated with allergic disease. Then 37 years elapsed before Loeffler's3 classic report appeared, and 47 years before tropical eosinophilia was described by Weingarten.4 The clinical description by Loeffler5 of transient pulmonary
REEDER WH, GOODRICH BE. PULMONARY INFILTRATION WITH EOSINOPHILIA (PIE SYNDROME)1. Ann Intern Med. ;36:1217–1240. doi: 10.7326/0003-4819-36-5-1217
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Published: Ann Intern Med. 1952;36(5):1217-1240.
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