A. E. DAGRADI, M.D.; N. SOLLOD, M.D.; J. H. FRIEDLANDER, M.D.
Since the original description by Boeck1 in 1899 of the histologic characteristics of the disease sarcoidosis, and the demonstration by Schaumann in 1914 that it can become generalized, with a particular predilection for the lymphohematopoietic system, an extensive literature has appeared on the subject. This has been reviewed recently in some detail by Freiman.2
Hepatic and/or splenic enlargement has been noted to occur clinically in a certain number of cases of Boeck's sarcoid, the incidence of liver enlargement being perhaps slightly less than that of splenic enlargement. The study of postmortem3, 4 and of biopsy material5, 6, 7 obtained from
DAGRADI AE, SOLLOD N, FRIEDLANDER JH. SARCOIDOSIS WITH MARKED HEPATOSPLENOMEGALY AND JAUNDICE: A CASE REPORT WITH BIOPSY FINDINGS(SARCOIDOSIS WITH MARKED HEPATOSPLENOMEGALY AND JAUNDICE: A CASE REPORT WITH BIOPSY FINDINGS*). Ann Intern Med. 1952;36:1317–1323. doi: 10.7326/0003-4819-36-5-1317
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Published: Ann Intern Med. 1952;36(5):1317-1323.
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