JOHN P. MERRILL; JOHN M. WELLER
The high incidence of chronic bromide intoxication has been repeatedly stressed in the literature.1, 2, 3, 4, 5 The presence of bromide in proprietary remedies which may be sold without prescription particularly lends itself to the prevalence of this clinical condition. Bromides in small doses cause sedation; in high doses, or with continued intake exceeding excretion, chronic poisoning may occur, in which mental and neurologic disturbances are the most prominent features. Delirium, hallucinations, confusion and disorientation may be present in severe cases.
The metabolism of the bromide ion is much like that of the chloride ion and, in a sense,
MERRILL JP, WELLER JM. TREATMENT OF BROMISM WITH THE ARTIFICIAL KIDNEY1. Ann Intern Med. ;37:186–190. doi: 10.7326/0003-4819-37-1-186
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Published: Ann Intern Med. 1952;37(1):186-190.
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