P. W. C.
Although great advances have been made in the past decade in the chemotherapy of tuberculosis, all the agents hitherto available have proved to be unsatisfactory in certain important respects. Of these streptomycin and its derivatives are by far the most effective. As is well known, these antibiotics will often arrest acute fulminant pulmonary infections as well as generalized (miliary) tuberculosis, which have been intractable to all other measures. Furthermore, the serious toxic effects of streptomycin have been markedly diminished by the current regimens utilizing occasional small doses (one gram two or three times a week), since it was found that
C. PW. THE USE OF ISONICOTINYL HYDRAZINES IN THE TREATMENT OF TUBERCULOSIS. Ann Intern Med. ;37:204–208. doi: 10.7326/0003-4819-37-1-204
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Published: Ann Intern Med. 1952;37(1):204-208.
Infectious Disease, Mycobacterial Infections.
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