MURIEL C. MEYERS; STANLEY MILLER; JAMES W. LINMAN; FRANK H. BETHELL, F.A.C.P.
ACTH and cortisone have been put to trial in the treatment of a variety of hematologic disorders, to emerge as agents of therapeutic importance in thrombocytopenic purpura and acquired hemolytic anemia. In discussing these conditions it is implied that reference is made to the so-called idiopathic forms of the disease.
Thrombocytopenic purpura assumes a variety of clinical forms, varying widely in severity but having in common hemorrhagic manifestations associated with thrombocytopenia, increased capillary fragility, prolonged bleeding time and defective clot retraction. The marrow is active and essentially normal. The clinical course may be acute and fulminating, active but stationary, or
MEYERS MC, MILLER S, LINMAN JW, BETHELL FH. THE USE OF ACTH AND CORTISONE IN IDIOPATHIC THROMBOCYTOPENIC PURPURA AND IDIOPATHIC ACQUIRED HEMOLYTIC ANEMIA1. Ann Intern Med. ;37:352–361. doi: 10.7326/0003-4819-37-2-352
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Published: Ann Intern Med. 1952;37(2):352-361.
Coagulopathies, Hematology/Oncology, Platelet Disorders, Red Cell Disorders.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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