JOSEPH K. FREILICH, M.D.
The clinical entity of acute nonspecific pericarditis has been clearly defined.1, 2, 3 It is characterized by a history of an antecedent respiratory infection, followed after an interval of from several days to several weeks by the development of the signs and symptoms of pericarditis with effusion. These consist of paroxysmal substernal or precordial pains, usually severe, and usually aggravated by coughing, deep breathing or motion. In addition, one finds fever, leukocytosis, increased sedimentation rate and a pericardial friction rub. An associated pneumonitis or pleural effusion is not uncommon. There are characteristic electrocardiographic changes consisting of RS-T elevations and T
FREILICH JK. ACUTE NONSPECIFIC PERICARDITIS COMPLICATED BY THE DEVELOPMENT OF A FIBROUS PERICARDIUM1. Ann Intern Med. 1952;37:388–393. doi: 10.7326/0003-4819-37-2-388
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Published: Ann Intern Med. 1952;37(2):388-393.
Cardiology, Pericardial Disease.
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