MILTON S. SACKS, M.D.
After many years of fruitless investigation, from a therapeutic standpoint, of the etiology and control of acute leukemia, a small break in the completely dark horizon occurred in 1948 with the introduction of the folic acid antagonists.1 This was followed, in 1950, by observations that the hormones ACTH and cortisone also exerted a temporary beneficial effect upon certain types of acute leukemia.2 From the mass of literature which has accumulated in the past four years a few facts have emerged and become crystallized. It is quite apparent that these are but the veriest beginnings of an understanding of this inexorably
SACKS MS. THE PRESENT STATUS OF THERAPY IN ACUTE LEUKEMIA. Ann Intern Med. 1952;37:400–403. doi: 10.7326/0003-4819-37-2-400
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Published: Ann Intern Med. 1952;37(2):400-403.
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