R. H. EBERT; W. R. BARCLAY
Cortisone and adrenocorticotropic hormone (ACTH) have a profound effect on a variety of inflammatory reactions, including acute and chronic infections,1, 2 wound healing,3 the Shwartzman phenomenon,4 chemical irritation5 and thermal burns.6 In an effort to elucidate the nature of the changes which occur during cortisone therapy, a series of in vivo studies was undertaken using the rabbit ear chamber technic. Since earlier work in this laboratory using the rabbit ear chamber technic as an in vivo method of observation had provided insight into the dynamics of certain inflammatory reactions and hypersensitive states, it was felt that a study of the
EBERT RH, BARCLAY WR. CHANGES IN CONNECTIVE TISSUE REACTION INDUCED BY CORTISONE1. Ann Intern Med. ;37:506–518. doi: 10.7326/0003-4819-37-3-506
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Published: Ann Intern Med. 1952;37(3):506-518.
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