RALPH E. HIBBS, M.D., F.A.C.P.; HOMER P. RUSH, M.D., F.A.C.P.
Albright's syndrome1 is characterized by brown pigmentation of the skin, a cystic disease of the bone and precocious puberty in females. It is a rare disease—less than 50 cases of the complete syndrome have been reported to date. Other terms used to describe this disease include polyostotic fibrous dysplasia, brown spot syndrome and osteitis fibrosa disseminata. Its importance lies in the recognition of the bone lesions and their differentiation from those of hyperparathyroidism and other cystic diseases of the bone. If Albright's syndrome is present, an operation on the parathyroids can be avoided, since these glands are not involved in
HIBBS RE, RUSH HP. ALBRIGHT'S SYNDROME1. Ann Intern Med. ;37:587–593. doi: 10.7326/0003-4819-37-3-587
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Published: Ann Intern Med. 1952;37(3):587-593.
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