RAYMOND S. JACKSON, M.D.; CHARLES F. WILKINSON JR., M.D., F.A.C.P.
Atherosclerosis has come to be recognized as a disease which is not an inevitable result of vascular aging, but rather an episodic process which may be to some extent reversible. Because of this, there have been many attempts to identify measurable abnormalities which could be employed to detect this tendency in its earliest stages.1-15 One of the most recent of these is the ratio between phospholipid and total cholesterol in the blood serum. The evidence in favor of this ratio as the circulating symbol of atherosclerosis might be summed up as follows:
There is a decrease in the ratio, phospholipid
JACKSON RS, WILKINSON CF. THE RATIO BETWEEN PHOSPHOLIPID AND THE CHOLESTEROLS IN PLASMA AS AN INDEX OF HUMAN ATHEROSCLEROSIS1. Ann Intern Med. ;37:1162–1171. doi: 10.7326/0003-4819-37-6-1162
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Published: Ann Intern Med. 1952;37(6):1162-1171.
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