EDWARD S. RAY, M.D., F.A.C.P.; HUGH P. FISHER JR., M.D.
Hypertrophic osteoarthropathy has interested internists since the latter part of the Nineteenth Century, when Marie1 and Bamberger2 independently reported the presence of osteitis of the long bones of the extremities associated with pulmonary disease. Since that time, similar bone changes have been reported in many disease processes.
Although chronic pulmonary disease3, 4, 5, 6, 7 has been the most frequent cause of osteoarthropathy, these bone changes have been frequently noted in cases of congenital heart disease,4, 13 arteriovenous fistula and subacute bacterial endocarditis14; less frequently it has been described in cases of chronic liver disease,4 chronic infections of the
RAY ES, FISHER HP. HYPERTROPHIC OSTEOARTHROPATHY IN PULMONARY MALIGNANCIES1. Ann Intern Med. ;38:239–246. doi: 10.7326/0003-4819-38-2-239
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Published: Ann Intern Med. 1953;38(2):239-246.
Hematology/Oncology, Pulmonary/Critical Care.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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