STUART W. COSGRIFF, M.D.
Major arterial occlusions by emboli constitute one of the serious complications encountered in patients with chronic cardiac disease, particularly in individuals with inactive rheumatic mitral stenosis. Clinically recognizable embolism occurs in from 4 to 8 per cent of patients with chronic rheumatic heart disease,1, 2 and 60 per cent of these experience multiple episodes of vascular occlusion. In individuals with multiple embolism 75 per cent of the recurrences take place within one year of the initial episode.3
Mural thrombus formations in one or more chambers are found in between 13 and 56 per cent of the autopsy examinations of patients
COSGRIFF SW. CHRONIC ANTICOAGULANT THERAPY IN RECURRENT EMBOLISM OF CARDIAC ORIGIN1. Ann Intern Med. ;38:278–287. doi: 10.7326/0003-4819-38-2-278
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Published: Ann Intern Med. 1953;38(2):278-287.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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