CHARLES LEROY STEINBERG, B.S., M.D., F.A.C.P.
The purpose of this paper is to suggest a new cause and effect for the beneficial sequelae produced by splenectomy in Felty's syndrome. Felty1 described a syndrome of mild rheumatoid arthritis associated with fever, secondary anemia (in four of five cases reported), leukopenia ranging from 1,000 to 4,200 leukocytes, splenomegaly and tachycardia. Rheumatologists are practically unanimous in believing that this syndrome is a variant of rheumatoid arthritis.
Forty-six papers1-46 have been published on the value of splenectomy in rheumatoid arthritis; 37 patients have been described in these papers as having undergone splenectomy successfully. The effects of splenectomy in these cases
STEINBERG CL. SPLENECTOMY IN RHEUMATOID ARTHRITIS1. Ann Intern Med. 1953;38:787–813. doi: 10.7326/0003-4819-38-4-787
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Published: Ann Intern Med. 1953;38(4):787-813.
Rheumatoid Arthritis, Rheumatology.
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