GEORGE W. MELLINGER, M.D.; CLARENCE C. PEARSON, M.D., F.A.C.P.
Acute porphyria is an inborn or acquired error of metabolism characterized by the urinary excretion of abnormal quantities of uroporphyrin, coproporphyrin and porphobilinogen, and manifested clinically by intermittent attacks of acute abdominal pain, constipation, neurologic symptoms or psychic disturbances. The varied clinical features, as well as the pathologic chemistry of the condition, have been adequately reviewed,1, 2, 3, 4, 5 and the present authors can add nothing to these excellent presentations. One point deserves emphasis, however. Acute porphyria may present such varied symptoms that the diagnosis is often not considered for several years after the onset.6 The test for urinary
MELLINGER GW, PEARSON CC. ACUTE PORPHYRIA: A CASE REPORT1. Ann Intern Med. ;38:862–868. doi: 10.7326/0003-4819-38-4-862
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Published: Ann Intern Med. 1953;38(4):862-868.
Gastroenterology/Hepatology, Liver Disease.
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