Recent investigations have led to the discovery of a number of new antigen systems in the human red cell. With the steadily increasing employment of blood transfusions in clinical medicine it is essential that the significance of this new information be evaluated. Of primary importance is the concept of the antigen system. A period of 27 years elapsed between the discovery of the related antigens A and B and the antigens M and N. Genetic studies had already led to the development of a valid theory of inheritance of the A and B antigens. Similar studies soon revealed a specific
NEW RED CELL ANTIGENS: THEIR SIGNIFICANCE IN TRANSFUSION THERAPY. Ann Intern Med. ;38:886–889. doi: 10.7326/0003-4819-38-4-886
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Published: Ann Intern Med. 1953;38(4):886-889.
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