DONALD F. GIBBS, M.B., M.R.C.P.E.; NEIL MACLEAN, M.B., Ch.B., D.P.H., M.R.C.P.E.
The successful surgical removal of a benign pheochromocytoma results usually in radical cure of the associated hypertension. The recognition of this condition, and its isolation from other forms of hypertension, therefore assume an importance out of proportion to its frequency.
The clinical features vary considerably. Such tumors may be associated with classic paroxysmal hypertension. Excessive sweating, palpitation, peripheral vasospastic episodes, and features suggestive of thyrotoxicosis or "anxiety states" should, in the presence of hypertension, arouse suspicion, and they are fully discussed by Smithwick.1 Diminished carbohydrate tolerance, postural hypotension and tachycardia, unexplained pyrexia and a high metabolic rate may also be
GIBBS DF, MACLEAN N. EXTRAADRENAL PHEOCHROMOCYTOMAS EXHIBITING A FALSE-NEGATIVE F 933 TEST1. Ann Intern Med. 1953;38:1069–1080. doi: 10.7326/0003-4819-38-5-1069
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Published: Ann Intern Med. 1953;38(5):1069-1080.
Adrenal Disorders, Endocrine and Metabolism, Endocrine Cancer, Hematology/Oncology.
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