EDMUND L. DUBOIS, M.D.
Five years have passed since Hargraves described the L. E. (lupus erythematosus) cell,1 and during that period there has been a profound change in the concept of systemic lupus erythematosus. It is the purpose of this paper to point out the pleomorphism of this relatively common disease, which occurs with one-half the incidence of acute rheumatic fever at the Los Angeles County General Hospital. There is no classic pattern of this illness, and the diagnosis must be based on an over-all view of the entire clinical picture with the aid of the L. E. test.2, 3 Because of its varied
DUBOIS EL. THE EFFECT OF THE L. E. CELL TEST ON THE CLINICAL PICTURE OF SYSTEMIC LUPUS ERYTHEMATOSUS1. Ann Intern Med. ;38:1265–1294. doi: 10.7326/0003-4819-38-6-1265
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Published: Ann Intern Med. 1953;38(6):1265-1294.
Lupus Erythematosus, Rheumatology.
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