WILLIAM B. PARSONS JR., M.D.; TALBERT COOPER, M.D., F.A.C.P.; CHARLES H. SCHEIFLEY, M.D., F.A.C.P.
Anemia of variable degree is the commonest hematologic abnormality observed in subacute bacterial endocarditis. The erythrocytes are usually somewhat hypochromic but may be normochromic. Usually the leukocytes are normal in number, but they may be increased, particularly if embolic complications are present. Morphologically, "toxic" changes are apparent in the granulocytes, sometimes accompanied by a shift to the left. The number of platelets has not been consistently altered in cases reported in the literature. The presence of phagocytic reticuloendothelial cells in stained smears of peripheral blood has been demonstrated by many observers in about 15 per cent of cases. Although these
PARSONS WB, COOPER T, SCHEIFLEY CH. OCCULT SUBACUTE BACTERIAL ENDOCARDITIS MANIFESTED BY HEMATOLOGIC ABNORMALITIES, INCLUDING PANCYTOPENIA1. Ann Intern Med. ;39:318–325. doi: 10.7326/0003-4819-39-2-318
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Published: Ann Intern Med. 1953;39(2):318-325.
Cardiology, Endocarditis, Hematology/Oncology, Infectious Disease, Streptococcal Infections.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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