H. W. ALLISON, M.D., (M.SC.(Med.)); T. L. BLISS, M.D., F.A.C.P.
Patients with cardiovascular disease accompanied by signs or symptoms suggesting hyperactive thyroid function are frequently encountered. In some instances, especially when goiter is present, careful study leaves an inconclusive clinical impression on which treatment is based. The deficiencies in the basal metabolism determination in evaluation of thyroid activity in hypermetabolic states of other origin prevent its being a decisive factor in differential diagnosis in some of these cases. This study was performed to learn whether the determination of the protein-bound iodine would provide a more satisfactory objective aid in diagnosis in such cases, so that proper cardiovascular treatment would be
ALLISON HW, BLISS TL. PROTEIN-BOUND BLOOD IODINE IN CARDIOVASCULAR DISEASE1. Ann Intern Med. ;39:326–332. doi: 10.7326/0003-4819-39-2-326
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Published: Ann Intern Med. 1953;39(2):326-332.
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