MALCOLM C. MCCORD; JOHN MOBERLY
Generalized hypertrophic osteo-arthropathy may cause a definite symptom complex entirely apart from, and often preceding, the symptoms arising from the primary disease. This symptomatic state was clearly described in the initial reports of this interesting disease process. The patient presented by Bamberger in 18891 and, with additions, in 1891,2 and the patients described by Marie in 1890,3 evidenced arthritis and deforming skeletal changes. The term applied by Marie to this lesion, "osteo-arthropathie hypertrophiante pneumique," in itself indicates the emphasis placed on the bone and joint manifestations with enlargement of the extremities. The early reports by the English physicians Thorburn,4 Godlee5
MCCORD MC, MOBERLY J. ACUTE HYPERTROPHIC OSTEO-ARTHROPATHY ASSOCIATED WITH SUBACUTE BACTERIAL ENDOCARDITIS(ACUTE HYPERTROPHIC OSTEO-ARTHROPATHY ASSOCIATED WITH SUBACUTE BACTERIAL ENDOCARDITIS*). Ann Intern Med. 1953;39:640–643. doi: 10.7326/0003-4819-39-3-640
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Published: Ann Intern Med. 1953;39(3):640-643.
Cardiology, Endocarditis, Infectious Disease, Streptococcal Infections.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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