GEORGE L. WALDBOTT, M.D., F.A.C.P.
The literature concerning the effect of tobacco on the human organism is mainly concerned with the cardiovascular system. In a review on the subject, Scott1 notes that during smoking the blood pressure shows a transient rise, averaging 15 mm., the pulse rate increases about eight beats a minute, and skin temperature falls due to capillary constriction. Bryant and Wood2 observed the occurrence of anginal pains from smoking. Smoking is believed by some to be responsible for the occurrence of thromboangiitis obliterans.
Relative to the respiratory tract, there is some evidence—and much speculation—that smoking contributes to the development of lung cancer.
WALDBOTT GL. FURTHER OBSERVATIONS ON SMOKER'S RESPIRATORY SYNDROME(FURTHER OBSERVATIONS ON SMOKER'S RESPIRATORY SYNDROME*). Ann Intern Med. 1953;39:1026–1031. doi: 10.7326/0003-4819-39-5-1026
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Published: Ann Intern Med. 1953;39(5):1026-1031.
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