JOSEPH I. GOODMAN, M.D., F.A.C.P.
It was fully recognized in the older literature that the liver is frequently increased in size, and sometimes tender, in patients with diabetes mellitus.1-3 In fact, in 1885 Pavy4 found liver enlargement associated with diabetes often enough to warrant his postulating a connection between the two conditions. However, in the recent clinical literature there have been relatively few references to hepatic enlargement in diabetes mellitus.5-7, 14, 18, 32, 36 Of more pertinent value in this respect are the reports of animal experiments. Following total extirpation of the pancreas in dogs the liver remains large out of all proportion to the
GOODMAN JI. HEPATOMEGALY AND DIABETES MELLITUS1. Ann Intern Med. ;39:1077–1087. doi: 10.7326/0003-4819-39-5-1077
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Published: Ann Intern Med. 1953;39(5):1077-1087.
Cardiology, Coronary Risk Factors, Diabetes, Endocrine and Metabolism.
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