ISIDOR MUFSON, M.D., F.A.C.P.
When the etiology of a disease is unknown its treatment is at best haphazard. This has heretofore been the fate of Raynaud's disease and scleroderma. From an analysis of clinical material,5 we concluded that the vasospasm of minute vessels which characterizes Raynaud's disease is the somatic manifestation of a chronic psychologic derangement. This viewpoint has since found support.3, 9 At that time evidence was available that scleroderma had the same origin. We now present analyses of our clinical findings which make more evident the relationship of Raynaud's disease to scleroderma. They are one disease, and differ only in the intensity
MUFSON I. AN ETIOLOGY OF SCLERODERMA1. Ann Intern Med. ;39:1219–1227. doi: 10.7326/0003-4819-39-6-1219
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Published: Ann Intern Med. 1953;39(6):1219-1227.
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