KENNETH F. GOLDEN, M.D.; JOHN T. PRIOR, M.D.
A characteristic type of renal tubular epithelial damage has been described in both man and experimental animals following the intravenous administration of hypertonic sucrose solutions. This kidney lesion, generally known as "sucrose nephrosis," has been observed in association with other sugars in hypertonic solution including xylose, inulin and glucose. It has also been reported to have occurred in man following such substances in hypertonic solutions as acacia, creatinine, sodium sulfate and urea. Although repeated injections of hypertonic sucrose at frequent intervals can effect significant interference with renal function in man, it is generally considered that the renal lesion produced by
GOLDEN KF, PRIOR JT. GLUCOSE NEPHROSIS WITH RENAL FAILURE IN A PATIENT WITH LAENNEC'S CIRRHOSIS(GLUCOSE NEPHROSIS WITH RENAL FAILURE IN A PATIENT WITH LAENNEC'S CIRRHOSIS*). Ann Intern Med. 1953;39:1308–1315. doi: 10.7326/0003-4819-39-6-1308
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Published: Ann Intern Med. 1953;39(6):1308-1315.
Gastroenterology/Hepatology, Liver Disease, Nephrology, Nephrotic Syndrome.
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