RAFAEL RODRIGUEZ-MOLINA, F.A.C.P.
Sprue is a chronic, wasting disease which, in the light of modern medical science, is classified among the deficiency states. Medical literature during the past 20 years has not significantly altered the basic concepts about sprue. Recent observations, however, have contributed materially to a better understanding of the etiologic factors, diagnostic criteria and effective treatment of this interesting syndrome.1, 2, 3, 4 In the earlier writings5, 6 great importance was ascribed to the differential diagnosis between sprue and addisonian or pernicious anemia of temperate climates. Mainly through the work of Castle, Rhoads and associates, we now consider these conditions closely
RODRIGUEZ-MOLINA R. FUNDAMENTAL CONCEPTS IN THE DIAGNOSIS OF SPRUE1. Ann Intern Med. ;40:33–41. doi: 10.7326/0003-4819-40-1-33
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Published: Ann Intern Med. 1954;40(1):33-41.
Celiac Disease and Malabsorption, Gastroenterology/Hepatology.
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