RAYMOND M. BURGISON
Although morphine has been one of the most important drugs in the physician's armamentarium for many years, its serious disadvantages have always been recognized. Along with the dangers inherent in overdosage of the drug, serious side effects have limited its usefulness—depression of the respiration, slowing and weakness of the pulse, constipation, nausea and vomiting, excitation in some individuals and the ever present danger of addiction.
Because of these disadvantages and the virtual indispensability of morphine for the relief of severe pain, many attempts have been made to find substitutes possessing the analgesic properties of morphine but devoid of its serious
RAYMOND M. BURGISON. NALORPHINE HYDROCHLORIDE, N.N.R. ("NALLINE HYDROCHLORIDE"). Ann Intern Med. 1954;40:183–186. doi: 10.7326/0003-4819-40-1-183
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Published: Ann Intern Med. 1954;40(1):183-186.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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