JOHN A. PRIOR, M.D., F.A.C.P.; SAMUEL SASLAW, M.D., Ph.D.; CLARENCE R. COLE, D.V.M.
Histoplasmosis, which previously had been considered to be a rare and fatal disease, is not now of infrequent occurrence especially in the middle western United States. It has been shown that the endemic center of histoplasmosis coincides with the region of high incidence of (1) pulmonary calcifications,1 and (2) histoplasmin skin reactors.2 Our studies in Ohio3, 4, 5 have shown that within the state there is a definite pattern for proved cases of histoplasmosis that coincides with the distribution of histoplasmin reactors and pulmonary calcifications. This demonstrated correlation of skin test, pulmonary calcifications and proved cases suggests that the histoplasmin
PRIOR JA, SASLAW S, COLE CR. EXPERIENCES WITH HISTOPLASMOSIS1. Ann Intern Med. ;40:221–244. doi: 10.7326/0003-4819-40-2-221
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Published: Ann Intern Med. 1954;40(2):221-244.
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