JUNE F. KLINGHOFFER, M.D.
Evidence indicating that Löffler's syndrome is a manifestation of an allergic reaction in the lung tissue is steadily accumulating. From the time of its original description by Löffler1 in 1932, this syndrome of transitory pulmonary infiltrations associated with blood eosinophilia received much attention in European countries; it has been only in the past five years that American medical literature has reflected an equal degree of interest.
Löffler and his co-workers2 reproduced the syndrome in the guinea pig by the administration of ascaris eggs, and early reports stressed the relationship of this syndrome to parasitic infestation,3, 4, 5, 6, 7 especially
KLINGHOFFER JF. LÖFFLER'S SYNDROME FOLLOWING USE OF A VAGINAL CREAM1. Ann Intern Med. ;40:343–350. doi: 10.7326/0003-4819-40-2-343
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Published: Ann Intern Med. 1954;40(2):343-350.
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