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Bürger undertakes to contrast clinical impressions against diagnoses established by the direct examination of structures by the pathologist or surgeon. He attacks the important art of differential diagnosis by throwing into relief the commonest mistakes in interpretation of the symptoms and signs offered by diseases in each organ system.
The author first discusses the limitations of the various procedures, including physical examination and not neglecting intuition, leading to clinical impressions. He discusses the fallibility of supposedly purely objective criteria offered by the laboratory. "Negative" tests in the face of patent disease must be repeated or discarded. The occasional "positive" test
Klinische Fehldiagnosen.. Ann Intern Med. ;40:381–383. doi: 10.7326/0003-4819-40-2-381
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Published: Ann Intern Med. 1954;40(2):381-383.
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