Hyaluronic acid has been isolated from the pleural or peritoneal fluid associated with mesothelioma by Meyer and Chaffee1 and Blix.2 In our case this finding led to the suspicion of the diagnosis of mesothelioma, later confirmed by the autopsy findings.
A 27 year old white female was admitted to the United States Army Hospital, Fort McClellan, Alabama, on May 1, 1952, for repair of a left inguinal hernia. Convalescence was uneventful, and she was discharged on May 8. Several days after discharge from the hospital the patient noted that her abdomen was enlarging. On May 10 she developed
DVOSKIN S. MESOTHELIOMA OF THE PERITONEUM: A CASE REPORT IN WHICH THE ASCITIC FLUID CONTAINED HYALURONIC ACID1. Ann Intern Med. ;40:809–811. doi: 10.7326/0003-4819-40-4-809
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Published: Ann Intern Med. 1954;40(4):809-811.
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