MARTIN S. KLECKNER JR., M.D.
It is recognized that accurate information derived from a thorough history and physical examination is unparalleled in importance to diagnose adequately diseases of the liver, and that data obtained from various hepatic function tests and needle biopsy of the liver may afford supplementary diagnostic information.1 In many cases of liver disease these tests have limited value, perhaps due to the complexity of the functions of the liver and their discrepancy with hepatic morphology. Tests of hepatic function designate a certain pattern rather than appraise true metabolic functions in liver disease.
Needle biopsy of the liver, when adequately performed, should
KLECKNER MS. NEEDLE BIOPSY OF THE LIVER: AN APPRAISAL OF ITS DIAGNOSTIC INDICATIONS AND LIMITATIONS1. Ann Intern Med. 1954;40:1177–1193. doi: 10.7326/0003-4819-40-6-1177
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Published: Ann Intern Med. 1954;40(6):1177-1193.
Gastroenterology/Hepatology, Liver Disease.
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