ERNEST BEUTLER, M.D.
Since Sadler's1 original description of leukemia in a patient with a "round cell sarcoma" there have been many reports of cases of malignant lymphoma terminating in leukemia. The dominant cell type of these leukemias has been a variety of mononuclears such as large lymphocytes or stem cells,2-7 small lymphocytes,5, 6, 8-12 "lymphosarcoma cells" or "leukosarcoma cells,"2, 13-18 unspecified types of mononuclears19-23 and monocytes.9 To our knowledge, however, no case of myelogenous leukemia has ever been reported in any patient with a malignant lymphoma.
A 19 year old male college student was admitted to The University of Chicago Clinics
BEUTLER E. THE DEVELOPMENT OF ACUTE MYELOGENOUS LEUKEMIA IN A PATIENT WITH RETICULUM CELL LYMPHOMA1. Ann Intern Med. ;40:1217–1222. doi: 10.7326/0003-4819-40-6-1217
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Published: Ann Intern Med. 1954;40(6):1217-1222.
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