THOMAS R. KELLY, M.D.; THEODORE L. BLISS, M.D., F.A.C.P.
The occurrence of a fulminating and fatal thyroid crisis subsequent to the withdrawal of propylthiouracil used to control hyperthyroidism is the basis of this report. The thyroid-blocking drugs have gained wide acceptance as a preparation for surgery and as a definitive method of treating hyperthyroidism. In the latter use its withdrawal may be followed by relapse after variable intervals. We were unable to find a report of thyroid crisis occurring at an interval subsequent to the withdrawal of a thyroid-blocking drug. Nelson et al.1 have reported death due to thyroid crisis a few days after the administration of radioactive iodine
KELLY TR, BLISS TL. THYROID CRISIS SUBSEQUENT TO WITHDRAWAL OF PROPYLTHIOURACIL1. Ann Intern Med. 1954;40:1223–1226. doi: 10.7326/0003-4819-40-6-1223
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Published: Ann Intern Med. 1954;40(6):1223-1226.
Endocrine and Metabolism, Thyroid Disorders.
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