PAUL W. CLOUGH
Although hemophilia is a relatively rare disease, its spectacular nature and its unusual clinical and genetic features have made it a subject of unusual interest both to the laity and to the medical profession. The disease has been recognized clinically for a century, and less definitive descriptions can be found in older writings back to the Talmud. Recent studies have amplified and modified some of our conceptions of the disease.
Hemophilia is commonly defined as a disorder characterized by a tendency to abnormally persistent bleeding, eventually often exsanguinating, and by a prolonged coagulation time, which is usually hereditary, confined (almost)
CLOUGH PW. HEMOPHILIA AND ALLIED DISORDERS. Ann Intern Med. ;40:1235–1241. doi: 10.7326/0003-4819-40-6-1235
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Published: Ann Intern Med. 1954;40(6):1235-1241.
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