DAVID H. APPELMAN, M.D.; GEORGE B. GORDON, M.D.
The development of acute hemolytic anemia during the course of infectious mononucleosis has only recently been reported.1-4 Dameshek and Schwartz5 had previously reported the occurrence of hemolytic anemia in a patient with infectious mononucleosis but in this instance, sulfadiazine had been administered. Ellis, Wollenman and Stetson1 described the occurrence of acute hemolytic anemia in an illness resembling infectious mononucleosis in which autohemagglutinins, hemolysins and a positive Donath-Landsteiner test were found. In their case the heterophil antibody titer was markedly elevated initially, as were the hemagglutinin titers. Coincident with the fall in the heterophil antibody titer a decrease in serum hemagglutinins
APPELMAN DH, GORDON GB. ACUTE HEMOLYTIC ANEMIA COMPLICATING INFECTIOUS MONONUCLEOSIS: REPORT OF TWO CASES1. Ann Intern Med. ;41:371–376. doi: 10.7326/0003-4819-41-2-371
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Published: Ann Intern Med. 1954;41(2):371-376.
Hematology/Oncology, Infectious Disease, Red Cell Disorders.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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