KIESL KAUFMAN, M.D.
The purpose of this study was to evaluate the serum cholinesterase activity as a test of liver function. Previous investigators, using various technical procedures, reported a wide range of normal values. They indicated, however, that the test had considerable merit, since it appeared to be a direct test of liver function which did not depend on any abnormality of the protein fractions.
Brauer and Root1 and Ellis, Sanders, Shirley and Bodansky2 showed that when rat livers were damaged by carbon tetrachloride the serum cholinesterase was lowered. This finding would suggest that the enzyme was
KAUFMAN K. SERUM CHOLINESTERASE ACTIVITY IN THE NORMAL INDIVIDUAL AND IN PEOPLE WITH LIVER DISEASE(SERUM CHOLINESTERASE ACTIVITY IN THE NORMAL INDIVIDUAL AND IN PEOPLE WITH LIVER DISEASE*). Ann Intern Med. 1954;41:533–545. doi: 10.7326/0003-4819-41-3-533
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Published: Ann Intern Med. 1954;41(3):533-545.
Gastroenterology/Hepatology, Liver Disease.
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