HELMUTH SPRINZ; ROBERT S. NELSON
The more frequent use of needle biopsies in the diagnosis of liver disease has led to the clarification of the pathogenesis in many known clinical conditions. It might be expected that the widespread employment of this procedure would also uncover certain histologic findings which, together with the clinical picture, could not be readily explained under previous concepts. In a total of 630 needle biopsies of the liver performed on the Medical Service of the 98th General Hospital, Munich, Germany, two instances have been noted of unusual biopsy findings which, in our experience, showed no correlation with the initial clinical evaluation
SPRINZ H, NELSON RS. PERSISTENT NONHEMOLYTIC HYPERBILIRUBINEMIA ASSOCIATED WITH LIPOCHROMELIKE PIGMENT IN LIVER CELLS: REPORT OF FOUR CASES1. Ann Intern Med. ;41:952–962. doi: 10.7326/0003-4819-41-5-952
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Published: Ann Intern Med. 1954;41(5):952-962.
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