HAROLD R. HIPP, M.D.; CARROLL F. SHUKERS, M.D.
Myoglobinuria is a disease characterized by the appearance in the urine of myoglobin, a protein resembling hemoglobin found in the muscle sarcoplasm. Four different forms have been recognized:1
1. Myoglobinuria associated with crushing injuries, many cases of which have been reported since interest was aroused in this syndrome by Bywaters.2
2. Haff disease, described in residents living near the sea inlet or Haff in Königsberg, Germany. This disease is supposedly caused by the ingestion of fish or eels poisoned by waste products from nearby cellulose factories.
3. Paralytic myoglobinuria occurring in work horses, which develop the disease on resuming work
HIPP HR, SHUKERS CF. SPONTANEOUS MYOGLOBINURIA: REPORT OF A CASE WITH SYMPTOMS OF MYOTONIA1. Ann Intern Med. 1955;42:197–200. doi: 10.7326/0003-4819-42-1-197
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Published: Ann Intern Med. 1955;42(1):197-200.
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