GEORGE V. LEROY, M.D.
Isotopes can be used in clinical research in two principal ways: first, to simplify existing analytic or diagnostic methods; and second, to study phenomena that cannot be examined readily, if at all, by conventional biochemical methods. There is no really good reason for considering the first option less important than the second, especially if the use of radioisotopes permits one to do more work, or to do it more accurately. It is easy, however, to become fascinated with the technical or electronic aspects of isotopes to the extent that interest in the physiologic problem is subordinated. It is possible to
LEROY GV. CLINICAL RESEARCH USING COMPOUNDS LABELED WITH RADIOACTIVE CARBON AND HYDROGEN AS TRACERS1. Ann Intern Med. ;42:239–250. doi: 10.7326/0003-4819-42-2-239
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Published: Ann Intern Med. 1955;42(2):239-250.
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