PAUL J. BILKA, M.D.; MAX H. WEIL, M.D.
Since the introduction by Hench1 of cortisone and corticotropin to clinical medicine, the value of these agents in certain acute disorders has been widely accepted. Their helpfulness and, at times, lifesaving nature are recognized. When they are administered for short periods the problem of "toxicity" or adverse physiologic effects of these hormones is minimal and is usually greatly overbalanced by their beneficial effects. However, in the treatment of a chronic disorder such as rheumatoid arthritis, where continued administration of the potent physiologic agent is required in order to maintain its benefits, the clinician is forced to ask himself the question:
BILKA PJ, WEIL MH. GOLD-HORMONAL THERAPY IN RHEUMATOID ARTHRITIS1. Ann Intern Med. 1955;42:638–643. doi: 10.7326/0003-4819-42-3-638
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Published: Ann Intern Med. 1955;42(3):638-643.
Rheumatoid Arthritis, Rheumatology.
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