F. G. HOFFMAN; DAVID ROSENBAUM, M.D.; P. D. GENOVESE, M.D.
In 1936 Löffler published a report of two patients with a hitherto unclassified type of endocarditis.1, 9 This entity, subsequently referred to as fibroplastic endocarditis or Löffler's endocarditis parietalis fibroplastica, is characterized by an afebrile course, progressive, refractory congestive failure and a striking eosinophilia. The cases reported by Löffler, in addition, exhibited signs of mitral valvulitis, though these were inadequate to account for the clinical picture.
Until 1948 only six cases had been reported, all in the Swiss and German literature. Lennox2 called attention to this entity and published a report of a possible early stage of Löffler's endocarditis.
HOFFMAN FG, ROSENBAUM D, GENOVESE PD. FIBROPLASTIC ENDOCARDITIS WITH EOSINOPHILIA (LÖFFLER'S ENDOCARDITIS PARIETALIS FIBROPLASTICA): CASE REPORT AND REVIEW OF LITERATURE1. Ann Intern Med. ;42:668–680. doi: 10.7326/0003-4819-42-3-668
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Published: Ann Intern Med. 1955;42(3):668-680.
Cardiology, Endocarditis, Infectious Disease.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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